Allakos Inc

NASDAQ:ALLKUnited States

Allakos Inc. is a clinical-stage biotechnology company, which is engaged in the development of therapeutics that target immunomodulatory receptors present on immune effector cells involved in allergy, inflammatory and proliferative diseases. The Company’s most advanced product candidate, AK006, is in a Phase I clinical trial. AK006 targets Siglec-6, an inhibitory receptor expressed selectively on mast cells. It is developing AK006 for the treatment of CSU and potentially other indications. AK006 has completed preclinical testing, and in these studies, it has demonstrated that binding of AK006 to Siglec-6 inhibits multiple modes of mast cell activation, including IgE, IL-33, KIT, C5a and MRGPR-X2. In addition to mast cell inhibition, AK006 reduced human tissue mast cells via ADCP in the presence of activated macrophages. The Company is also developing lirentelimab (AK002) and, in conjunction with the Phase II, lirentelimab results in atopic dermatitis and chronic spontaneous urticaria.

Contact Information

Headquarters

825 INDUSTRIAL ROAD, SUITE 500SAN CARLOS, CA, United States 94070

Phone

650-597-5002

Fax

302-655-5049

Executives

President

Adam Tomasi

Chief Executive Officer, Director

Robert Alexander

Chief Financial Officer

Baird Radford

Chief Medical Officer

Chin Lee

Independent Director

Robert Andreatta