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Company | Country | Symbol |
---|
Time | Volume | APLT |
---|---|---|
09:32 ET | 32706 | 9.07 |
09:33 ET | 2071 | 9.1 |
09:35 ET | 188906 | 9.025 |
09:37 ET | 520 | 8.95 |
09:39 ET | 4199 | 8.89 |
09:42 ET | 12828 | 8.77 |
09:44 ET | 3249 | 8.78 |
09:46 ET | 4130 | 8.74 |
09:48 ET | 43449 | 8.77 |
09:50 ET | 1840 | 8.85 |
09:51 ET | 5871 | 8.86 |
09:53 ET | 1340 | 8.84 |
09:55 ET | 12490 | 8.93 |
09:57 ET | 9532 | 8.955 |
10:00 ET | 2100 | 8.94 |
10:02 ET | 20544 | 8.9 |
10:04 ET | 839 | 8.865 |
10:06 ET | 600 | 8.865 |
10:08 ET | 7273 | 8.93 |
10:09 ET | 54200 | 8.825 |
10:11 ET | 14873 | 8.825 |
10:13 ET | 13649 | 8.845 |
10:15 ET | 704 | 8.89 |
10:18 ET | 4171 | 8.85 |
10:20 ET | 7600 | 8.885 |
10:22 ET | 9635 | 8.87 |
10:24 ET | 9356 | 8.88 |
10:26 ET | 2058 | 8.89 |
10:27 ET | 1193 | 8.96 |
10:29 ET | 3707 | 8.94 |
10:31 ET | 5978 | 8.97 |
10:33 ET | 2935 | 8.9 |
10:36 ET | 1209 | 8.905 |
10:38 ET | 3400 | 8.86 |
10:40 ET | 6448 | 8.92 |
10:42 ET | 65104 | 8.91 |
10:44 ET | 3017 | 8.88 |
10:45 ET | 13833 | 8.87 |
10:47 ET | 1212 | 8.89 |
10:49 ET | 9703 | 8.84 |
10:51 ET | 8270 | 8.86 |
10:54 ET | 5234 | 8.84 |
10:56 ET | 17624 | 8.83 |
10:58 ET | 2613 | 8.84 |
11:00 ET | 8755 | 8.8538 |
11:02 ET | 8768 | 8.82 |
11:03 ET | 100 | 8.82 |
11:05 ET | 7946 | 8.825 |
11:07 ET | 9436 | 8.84 |
11:09 ET | 4364 | 8.84 |
11:12 ET | 1069 | 8.82 |
11:14 ET | 900 | 8.81 |
11:16 ET | 2079 | 8.84 |
11:18 ET | 5728 | 8.87 |
11:20 ET | 3768 | 8.82 |
11:21 ET | 2721 | 8.84 |
11:23 ET | 3741 | 8.843432 |
11:25 ET | 8874 | 8.855 |
11:27 ET | 1500 | 8.825 |
11:30 ET | 400 | 8.825 |
11:32 ET | 300 | 8.825 |
11:34 ET | 4818 | 8.81 |
11:36 ET | 3173 | 8.8 |
11:38 ET | 1461 | 8.79 |
11:39 ET | 909 | 8.795 |
11:41 ET | 5071 | 8.78 |
11:43 ET | 1193 | 8.77 |
11:45 ET | 20000 | 8.75 |
11:48 ET | 7486 | 8.8 |
11:50 ET | 3225 | 8.77 |
11:52 ET | 1358 | 8.78 |
11:54 ET | 28423 | 8.8 |
11:56 ET | 100 | 8.8 |
11:57 ET | 320 | 8.8 |
11:59 ET | 1868 | 8.79 |
12:01 ET | 3226 | 8.81 |
12:03 ET | 1674 | 8.795 |
12:06 ET | 1266 | 8.782316 |
12:08 ET | 1822 | 8.791 |
12:10 ET | 4588 | 8.78 |
12:12 ET | 800 | 8.78 |
12:14 ET | 207 | 8.77 |
12:15 ET | 200 | 8.77 |
12:17 ET | 400 | 8.77 |
12:19 ET | 7523 | 8.8 |
12:21 ET | 526 | 8.81 |
12:24 ET | 2000 | 8.81 |
12:26 ET | 3565 | 8.8 |
12:28 ET | 3164 | 8.81 |
12:30 ET | 1864 | 8.8 |
12:32 ET | 951 | 8.8 |
12:35 ET | 100 | 8.81 |
12:37 ET | 846 | 8.79 |
12:39 ET | 1766 | 8.81 |
12:42 ET | 3373 | 8.79 |
12:44 ET | 400 | 8.78 |
12:46 ET | 830 | 8.785 |
12:48 ET | 1278 | 8.775 |
12:50 ET | 2218 | 8.78 |
12:51 ET | 200 | 8.78 |
12:53 ET | 9999 | 8.8 |
12:55 ET | 6656 | 8.78 |
12:57 ET | 222 | 8.775 |
01:00 ET | 7713 | 8.8 |
01:02 ET | 4866 | 8.8 |
01:04 ET | 15042 | 8.83 |
01:06 ET | 1040 | 8.82 |
01:08 ET | 4150 | 8.82 |
01:09 ET | 1200 | 8.82 |
01:11 ET | 2500 | 8.82 |
01:13 ET | 3114 | 8.81 |
01:15 ET | 3556 | 8.81 |
01:18 ET | 15415 | 8.85 |
01:20 ET | 2457 | 8.85 |
01:22 ET | 1600 | 8.85 |
01:24 ET | 3822 | 8.86 |
01:26 ET | 500 | 8.86 |
01:27 ET | 800 | 8.86 |
01:29 ET | 300 | 8.86 |
01:31 ET | 801 | 8.86 |
01:33 ET | 2757 | 8.915 |
01:36 ET | 16614 | 8.91 |
01:38 ET | 12249 | 8.95 |
01:40 ET | 2138 | 8.91 |
01:42 ET | 3891 | 8.89 |
01:44 ET | 46739 | 8.91 |
01:45 ET | 44615 | 8.885 |
01:47 ET | 1217 | 8.86 |
01:49 ET | 300 | 8.865 |
01:51 ET | 325 | 8.865 |
01:54 ET | 11942 | 8.855 |
01:56 ET | 1000 | 8.85 |
01:58 ET | 7007 | 8.85 |
02:00 ET | 15130 | 8.85 |
02:02 ET | 992 | 8.85 |
02:03 ET | 2670 | 8.845 |
02:05 ET | 5794 | 8.86 |
02:07 ET | 2146 | 8.86 |
02:09 ET | 400 | 8.86 |
02:12 ET | 1146 | 8.86 |
02:14 ET | 1462 | 8.85 |
02:16 ET | 3327 | 8.84 |
02:18 ET | 2688 | 8.83 |
02:20 ET | 430 | 8.83 |
02:21 ET | 20864 | 8.82 |
02:23 ET | 1011 | 8.825 |
02:25 ET | 4173 | 8.82 |
02:27 ET | 5283 | 8.82 |
02:30 ET | 14876 | 8.82 |
02:32 ET | 21361 | 8.74 |
02:34 ET | 1954 | 8.765 |
02:36 ET | 2594 | 8.76 |
02:38 ET | 796 | 8.76 |
02:39 ET | 3125 | 8.76 |
02:41 ET | 1106 | 8.76 |
02:43 ET | 3915 | 8.76 |
02:45 ET | 100 | 8.765 |
03:15 ET | 3608 | 8.7 |
03:17 ET | 4377 | 8.7 |
03:19 ET | 4338 | 8.71 |
03:21 ET | 3217 | 8.705 |
03:24 ET | 1431 | 8.715 |
03:26 ET | 3971 | 8.705 |
03:28 ET | 7262 | 8.76 |
03:30 ET | 4043 | 8.78 |
03:32 ET | 5446 | 8.79 |
03:33 ET | 3199 | 8.8 |
03:35 ET | 7321 | 8.75 |
03:37 ET | 3682 | 8.78 |
03:39 ET | 5608 | 8.77 |
03:42 ET | 5318 | 8.755 |
03:44 ET | 5721 | 8.725 |
03:46 ET | 1600 | 8.715 |
03:48 ET | 9194 | 8.75 |
03:50 ET | 5308 | 8.745 |
03:51 ET | 8288 | 8.735 |
03:53 ET | 12369 | 8.755 |
03:55 ET | 12441 | 8.72 |
03:57 ET | 22703 | 8.73 |
04:00 ET | 241587 | 8.69 |
Company sortable | Market Cap sortable | P/E Ratio (TTM) sortable | EPS Growth (5yr) sortable |
---|---|---|---|
Applied Therapeutics Inc | 998.0M | -5.7x | --- |
Bicara Therapeutics Inc | 987.7M | 0.0x | --- |
Cogent Biosciences Inc | 974.1M | -3.6x | --- |
Septerna Inc | 946.3M | -90,120.0x | --- |
Arrivent Biopharma Inc | 913.9M | -11.1x | --- |
LENZ Therapeutics Inc | 913.0M | -4.7x | --- |
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
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Market Cap | $998.0M |
---|---|
Revenue (TTM) | $-211.0K |
Shares Outstanding | 114.8M |
Dividend Yield | 0.00% |
Annual Dividend Rate | --- |
Ex-Dividend Date | 01-01-01 |
Pay Date | 01-01-01 |
Beta | 2.01 |
EPS | $-1.53 |
Book Value | $-0.20 |
P/E Ratio | -5.7x |
Price/Sales (TTM) | --- |
Price/Cash Flow (TTM) | --- |
Operating Margin | --- |
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