• LAST PRICE
    38.0300
  • TODAY'S CHANGE (%)
    0.0000 (0.0000%)
  • Bid / Lots
    36.3000/ 20
  • Ask / Lots
    38.2000/ 1
  • Open / Previous Close
    38.5800 / 38.0300
  • Day Range
    Low 37.9900
    High 38.9000
  • 52 Week Range
    Low 26.4100
    High 48.8200
  • Volume
    1,227,343
    average

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Price Comparison Graph. See accessible table below
1 Day Comparison Chart Accessibility Table. Monday's close: 38.98
TimeVolumeIONS
09:32 ET1578038.54
09:33 ET10038.56
09:35 ET53038.76
09:42 ET388838.81
09:46 ET107738.76
09:48 ET135438.81
09:50 ET100038.79
09:51 ET816738.75
09:53 ET180038.79
09:55 ET346738.77
09:57 ET125138.785
10:00 ET493338.75
10:02 ET190038.75
10:04 ET3798438.71
10:06 ET111638.76
10:08 ET30038.775
10:09 ET73738.86
10:11 ET41938.84
10:13 ET70038.62
10:15 ET100038.695
10:18 ET286038.65
10:20 ET164438.58
10:22 ET96138.63
10:24 ET263638.55
10:26 ET500638.43
10:27 ET276838.35
10:29 ET94538.35
10:31 ET150038.345
10:33 ET130038.45
10:36 ET186038.35
10:38 ET342838.265
10:40 ET866338.275
10:42 ET230038.305
10:44 ET70038.38
10:45 ET137238.43
10:49 ET204438.36
10:51 ET60038.33
10:54 ET80038.33
10:56 ET93538.25
10:58 ET30038.28
11:00 ET477438.25
11:02 ET353238.28
11:03 ET440038.3
11:05 ET41438.29
11:07 ET275038.245
11:09 ET1966138.23
11:12 ET790338.26
11:14 ET586438.245
11:16 ET507538.245
11:18 ET999238.25
11:20 ET75838.26
11:21 ET40038.265
11:23 ET40038.245
11:25 ET220038.1261
11:27 ET140338.2
11:30 ET10038.195
11:34 ET70038.26
11:36 ET10038.24
11:38 ET10038.23
11:39 ET100038.265
11:41 ET187738.2
11:43 ET90038.2
11:45 ET200238.25
11:48 ET164638.25
11:50 ET64438.25
11:52 ET149238.29
11:54 ET60038.25
11:56 ET70038.2516
11:57 ET160038.29
11:59 ET50038.26
12:01 ET90038.3
12:03 ET110038.26
12:06 ET20038.26
12:08 ET1585238.26
12:10 ET110038.31
12:12 ET100038.31
12:14 ET90238.3
12:15 ET154738.25
12:17 ET400538.26
12:19 ET90038.28
12:21 ET211238.26
12:24 ET110038.33
12:26 ET20038.29
12:28 ET82638.29
12:30 ET20038.315
12:32 ET20038.31
12:33 ET104538.2622
12:35 ET70038.25
12:37 ET110038.25
12:39 ET667538.26
12:42 ET386738.295
12:44 ET50038.285
12:46 ET112538.34
12:48 ET40038.32
12:50 ET90038.33
12:51 ET30038.3
12:53 ET176238.35
12:55 ET10038.32
12:57 ET70038.3
01:00 ET70038.29
01:02 ET50038.29
01:04 ET53838.29
01:06 ET116138.28
01:08 ET160038.25
01:09 ET420138.25
01:11 ET364538.25
01:13 ET155038.25
01:15 ET1077638.13
01:18 ET328538.205
01:20 ET188138.11
01:22 ET223938.02
01:24 ET562938.03
01:26 ET64838.02
01:27 ET345538.04
01:29 ET110038.08
01:31 ET89838.065
01:33 ET204338.06
01:36 ET150038.03
01:38 ET100038.02
01:40 ET392338.035
01:42 ET260038.06
01:44 ET320038.05
01:45 ET120038.05
01:47 ET160038.05
01:49 ET148038.05
01:51 ET234238.05
01:54 ET20038.05
01:56 ET254238.03
01:58 ET483438.045
02:00 ET60038.06
02:02 ET72038.04
02:03 ET203538.03
02:05 ET120038.08
02:07 ET140738.09
02:09 ET30038.13
02:12 ET82838.1
02:14 ET80838.13
02:16 ET214638.09
02:18 ET152738.14
02:20 ET101438.14
02:21 ET20038.14
02:23 ET120038.115
02:25 ET135738.11
02:27 ET110038.095
02:30 ET149038.02
02:32 ET193638.02
02:34 ET264238.045
02:36 ET60038.09
02:38 ET180038.07
02:39 ET96338.085
02:41 ET40038.08
02:45 ET197938.055
02:48 ET90038.04
02:50 ET70038.045
02:52 ET220138.03
02:54 ET111538.07
02:56 ET60038.06
02:57 ET20038.07
02:59 ET186638.07
03:01 ET220038.075
03:03 ET303038.03
03:06 ET90038.055
03:08 ET216338.005
03:10 ET346738
03:12 ET531438.02
03:14 ET309538.01
03:15 ET202138
03:17 ET267038.005
03:19 ET335438
03:21 ET665638
03:24 ET1070438.02
03:26 ET314238.1
03:28 ET200038.01
03:30 ET385638.045
03:32 ET205938.05
03:33 ET282938.03
03:35 ET515338.02
03:37 ET150038.01
03:39 ET646338.03
03:42 ET305238.01
03:44 ET375038.02
03:46 ET374638.05
03:48 ET326338.0527
03:50 ET413138.035
03:51 ET883538.07
03:53 ET822338.06
03:55 ET1922838
03:57 ET2125438.01
04:00 ET24576438.03
Data delayed at least 15 minutes.
Industry Peers Overview Table
Company sortableMarket Cap sortableP/E Ratio (TTM) sortableEPS Growth (5yr) sortable
United StatesIONS
Ionis Pharmaceuticals Inc
5.5B
656.7x
---
United StatesCRSP
CRISPR Therapeutics AG
4.1B
-5.8x
---
United StatesGH
Guardant Health Inc
5.3B
-8.3x
---
United StatesAZTA
Azenta Inc
4.5B
-389.3x
---
United StatesMEDP
Medpace Holdings Inc
6.4B
31.3x
+67.16%
United StatesMRVI
Maravai LifeSciences Holdings Inc
3.4B
5.3x
---
As of 2022-12-07

Company Information

Ionis Pharmaceuticals, Inc. is engaged in discovering and developing ribonucleic acid (RNA)-targeted therapeutics. The Company is primarily focused on our cardiovascular and neurology franchises. Its products include SPINRAZA, TEGSEDI and WAYLIVRA. SPINRAZA is for the treatment of patients of all ages with spinal muscular atrophy (SMA), a progressive, debilitating and often fatal genetic disease. TEGSEDI is for the treatment of patients with polyneuropathy caused by hereditary transthyretin (TTR), amyloidosis (hATTR), a debilitating, progressive, and fatal disease. WAYLIVRA is an antisense medicine indicated as an adjunct to diet in adult patients. The Company has over six medicines in Phase III studies for eight indications, which include Eplontersen (TTR), Olezarsen (ApoC-III), Donidalorsen (PKK), ION363 (FUS), Pelacarsen (Apo(a)) and Tofersen (SOD1). Its cardiovascular medicine in development includes Eplontersen, Olezarsen, Pelacarsen, ION449 (PCSK9), Fesomersen and IONIS-AGT-LRx.

Contact Information

Headquarters
2855 Gazelle CourtCARLSBAD, CA, United States 92010
Phone
760-931-9200
Fax
302-655-5049

Executives

Independent Chairman of the Board
Joseph Loscalzo
Chief Executive Officer, Director
Brett Monia
Chief Financial Officer, Executive Vice President - Finance
Elizabeth Hougen
Chief Scientific Officer
C. Frank Bennett
Executive Vice President, Chief Business Officer
Joseph Baroldi

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Fundamentals Table
Market Cap
$5.4B
Revenue (TTM)
$875.5M
Shares Outstanding
142.1M
Dividend Yield
0.00%
Annual Dividend Rate
---
Ex-Dividend Date
01-01-01
Pay Date
01-01-01
Beta
0.54
EPS
$0.06
Book Value
$5.47
P/E Ratio
656.7x
Price/Sales (TTM)
6.2
Price/Cash Flow (TTM)
217.3x
Operating Margin
2.11%
*GAAP = prior to non-GAAP analyst adjusted earnings.

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