MetaVia Inc

NASDAQ:MTVAUnited States

MetaVia Inc., formerly NeuroBo Pharmaceuticals, Inc., is a clinical-stage biotechnology company focused on transforming cardiometabolic diseases. It is developing DA-1726 for the treatment of obesity, and is developing DA-1241 for the treatment of Metabolic Dysfunction-Associated Steatohepatitis (MASH). DA-1726 is a novel oxyntomodulin (OXM) analogue that functions as a glucagon-like peptide-1 receptor (GLP1R) and glucagon receptor (GCGR) dual agonist. OXM is a naturally-occurring gut hormone that activates GLP1R and GCGR, thereby decreasing food intake while increasing energy expenditure, thus resulting in body weight loss compared to selective GLP1R agonists. DA-1241 is a novel G-Protein-Coupled Receptor 119 (GPR119) agonist with development optionality as a standalone and/or combination therapy for both MASH and type 2 diabetes. Agonism of GPR119 in the gut promotes the release of key gut peptides, GLP-1, glucagon-dependent insulinotropic polypeptide receptor, and peptide YY.

Contact Information

Headquarters

545 Concord Avenue, Suite 210CAMBRIDGE, MA, United States 02138

Phone

857-702-9600

Fax

734-293-0444

Executives

Independent Chairman of the Board

Andrew Koven

President, Chief Executive Officer, Director

Hyung Kim

Chief Financial Officer

Marshall Woodworth

Independent Director

Mark Glickman

Independent Director

Jason Groves