Alnylam Pharmaceuticals Inc

NASDAQ:ALNYUnited States

Alnylam Pharmaceuticals, Inc. is a clinical-stage company. The Company is engaged in developing mRNA cell therapies for the treatment of autoimmune diseases. The Company’s lead product candidate, Descartes-08, is an autologous mRNA CAR-T directed against the B cell maturation antigen (BCMA). Descartes-08 targets BCMA, which exists on the surface of long-lived plasma cells and plasmacytoid dendritic cells. Descartes-08 is in Phase IIb clinical development for patients with generalized myasthenia gravis (MG). Its other product candidate includes Descartes-15 and Descartes-33. Descartes-15 is a next-generation, autologous anti-BCMA mRNA CAR-T. Using its proprietary technology and manufacturing platform, it designed Descartes-15 to be more resistant than Descartes-08 to recycling of the CAR upon multiple antigen exposures. It is developing Descartes-33 to deliver a combination of therapeutic proteins that target key drivers in the pathogenesis of autoimmunity.

Contact Information

Headquarters

675 W Kendall StCAMBRIDGE, MA, United States 02142-1168

Phone

617-551-8200

Fax

617-551-8101

Executives

Independent Chairman of the Board

Amy Schulman

Chief Executive Officer, Director

Yvonne Greenstreet

Chief Financial Officer, Executive Vice President

Jeffrey Poulton

Executive Vice President, Chief Scientific Officer, Head - Early Research and Early Development

Kevin Fitzgerald

Chief Medical Officer, Executive Vice President - Development and Medical Affairs

Pushkal Garg