Ocuphire Pharma Inc

NASDAQ:OCUPUnited States

Ocuphire Pharma, Inc. is a clinical-stage biopharmaceutical company. The Company is focused on developing and commercializing therapies for the treatment of refractive and retinal eye disorders. The Company’s lead retinal product candidate, APX3330, is a small-molecule inhibitor of Ref-1 (reduction oxidation effector factor-1 protein). Ref1 is a regulator of transcription factors such as HIF-1α and NF-B. The Inhibiting REF-1 reduces levels of vascular endothelial growth factor (VEGF) and inflammatory cytokines which are known to play key roles in ocular angiogenesis and inflammation. APX3330 is an oral tablet to be administered twice per day for the treatment of DR. The Company’s pipeline candidates include APX2009 and APX2014. The Company is initially pursuing APX3330 for the DR indication as first-line therapy and may explore opportunities for clinical benefit as monotherapy or adjunctive therapy for other retinal indications such as DME, wAMD, and GA.

Contact Information

Headquarters

37000 Grand River Ave., Suite 120FARMINGTON HILLS, MI, United States 48335

Phone

248-681-9815

Fax

240-268-5310

Executives

Independent Chairman of the Board

Cam Gallagher

Chief Executive Officer, Director

George Magrath

Chief Financial Officer, Principal Financial Officer

Nirav Jhaveri

Chief Operating Officer

Joseph Schachle

Senior Vice President - Corporate Development and Operations

Bernhard Hoffmann