Applied Therapeutics IncNASDAQ:APLT
- LAST PRICE4.4400
- TODAY'S CHANGE (%)0.0000 (0.0000%)
- Bid / Lots---/ ---
- Ask / Lots---/ ---
- Open / Previous Close4.6500 / 4.4400
- Day Range
- 52 Week Range
- Volume1,099,427
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| Time | Volume | APLT |
|---|---|---|
| 09:32 ET | 5533 | 4.56 |
| 09:34 ET | 2268 | 4.59 |
| 09:36 ET | 1300 | 4.62 |
| 09:38 ET | 1546 | 4.64 |
| 09:39 ET | 1100 | 4.615 |
| 09:41 ET | 1602 | 4.59 |
| 09:43 ET | 600 | 4.55 |
| 09:45 ET | 200 | 4.54 |
| 09:48 ET | 1800 | 4.59 |
| 09:50 ET | 800 | 4.58 |
| 09:52 ET | 518 | 4.565 |
| 09:54 ET | 1263 | 4.57 |
| 09:56 ET | 100 | 4.57 |
| 09:57 ET | 900 | 4.56 |
| 09:59 ET | 644 | 4.57 |
| 10:01 ET | 1074 | 4.6 |
| 10:03 ET | 400 | 4.61 |
| 10:08 ET | 500 | 4.58 |
| 10:10 ET | 2338 | 4.6 |
| 10:12 ET | 606 | 4.6 |
| 10:14 ET | 858 | 4.59 |
| 10:15 ET | 717 | 4.57 |
| 10:17 ET | 1067 | 4.55 |
| 10:19 ET | 7454 | 4.6 |
| 10:21 ET | 300 | 4.59 |
| 10:24 ET | 200 | 4.6 |
| 10:28 ET | 200 | 4.6 |
| 10:30 ET | 5300 | 4.61 |
| 10:32 ET | 1463 | 4.599 |
| 10:33 ET | 2792 | 4.62 |
| 10:35 ET | 200 | 4.615 |
| 10:37 ET | 100 | 4.62 |
| 10:39 ET | 300 | 4.62 |
| 10:42 ET | 2372 | 4.58 |
| 10:44 ET | 200 | 4.585 |
| 10:48 ET | 400 | 4.59 |
| 10:50 ET | 300 | 4.58 |
| 10:51 ET | 341 | 4.58 |
| 10:53 ET | 734 | 4.58 |
| 10:55 ET | 100 | 4.575 |
| 10:57 ET | 300 | 4.57 |
| 11:00 ET | 200 | 4.57 |
| 11:02 ET | 3469 | 4.61 |
| 11:04 ET | 114 | 4.605 |
| 11:11 ET | 300 | 4.61 |
| 11:13 ET | 1964 | 4.6 |
| 11:15 ET | 100 | 4.605 |
| 11:18 ET | 1506 | 4.615 |
| 11:20 ET | 100 | 4.62 |
| 11:22 ET | 1373 | 4.61 |
| 11:24 ET | 2426 | 4.6 |
| 11:26 ET | 2321 | 4.62 |
| 11:29 ET | 1681 | 4.63 |
| 11:33 ET | 200 | 4.63 |
| 11:36 ET | 1573 | 4.63 |
| 11:40 ET | 100 | 4.635 |
| 11:42 ET | 33102 | 4.61 |
| 11:44 ET | 3400 | 4.6 |
| 11:45 ET | 100 | 4.6 |
| 11:47 ET | 1000 | 4.6 |
| 11:49 ET | 1412 | 4.6 |
| 11:51 ET | 600 | 4.6 |
| 11:54 ET | 400 | 4.605 |
| 11:56 ET | 200 | 4.605 |
| 11:58 ET | 2095 | 4.6 |
| 12:00 ET | 300 | 4.6 |
| 12:02 ET | 714 | 4.605 |
| 12:03 ET | 4853 | 4.61 |
| 12:05 ET | 300 | 4.61 |
| 12:07 ET | 100 | 4.6 |
| 12:09 ET | 100 | 4.605 |
| 12:12 ET | 2700 | 4.605 |
| 12:14 ET | 9754 | 4.61 |
| 12:16 ET | 1634 | 4.605 |
| 12:18 ET | 1766 | 4.605 |
| 12:20 ET | 1489 | 4.605 |
| 12:21 ET | 300 | 4.605 |
| 12:23 ET | 800 | 4.595 |
| 12:25 ET | 300 | 4.6 |
| 12:27 ET | 3127 | 4.604 |
| 12:32 ET | 1151 | 4.595 |
| 12:34 ET | 400 | 4.595 |
| 12:36 ET | 100 | 4.595 |
| 12:38 ET | 600 | 4.595 |
| 12:39 ET | 312 | 4.59 |
| 12:41 ET | 300 | 4.585 |
| 12:43 ET | 400 | 4.585 |
| 12:45 ET | 100 | 4.585 |
| 12:48 ET | 2379 | 4.59 |
| 12:50 ET | 3961 | 4.6001 |
| 12:54 ET | 24014 | 4.61 |
| 12:56 ET | 2716 | 4.574 |
| 12:57 ET | 709 | 4.575 |
| 12:59 ET | 200 | 4.57 |
| 01:01 ET | 1000 | 4.575 |
| 01:03 ET | 300 | 4.575 |
| 01:06 ET | 2443 | 4.58 |
| 01:10 ET | 714 | 4.575 |
| 01:14 ET | 400 | 4.5725 |
| 01:17 ET | 1427 | 4.58 |
| 01:19 ET | 1405 | 4.575 |
| 01:21 ET | 700 | 4.58 |
| 01:24 ET | 442 | 4.58 |
| 01:26 ET | 700 | 4.58 |
| 01:28 ET | 100 | 4.57 |
| 01:30 ET | 2264 | 4.575 |
| 01:32 ET | 300 | 4.57 |
| 01:33 ET | 3596 | 4.57 |
| 01:35 ET | 300 | 4.57 |
| 01:37 ET | 13986 | 4.605 |
| 01:42 ET | 4078 | 4.65 |
| 01:44 ET | 1411 | 4.6315 |
| 01:46 ET | 500 | 4.63 |
| 01:48 ET | 3083 | 4.625 |
| 01:50 ET | 794 | 4.62 |
| 01:51 ET | 1398 | 4.61 |
| 01:53 ET | 800 | 4.61 |
| 01:57 ET | 100 | 4.61 |
| 02:00 ET | 400 | 4.615 |
| 02:02 ET | 100 | 4.61 |
| 02:04 ET | 900 | 4.61 |
| 02:06 ET | 300 | 4.6 |
| 02:08 ET | 2826 | 4.605 |
| 02:09 ET | 5923 | 4.6011 |
| 02:11 ET | 500 | 4.61 |
| 02:13 ET | 125 | 4.605 |
| 02:15 ET | 2877 | 4.604 |
| 02:18 ET | 4182 | 4.61 |
| 02:20 ET | 600 | 4.62 |
| 02:22 ET | 200 | 4.615 |
| 02:24 ET | 3300 | 4.61 |
| 02:26 ET | 700 | 4.61 |
| 02:27 ET | 4160 | 4.6 |
| 02:29 ET | 500 | 4.6 |
| 02:31 ET | 1013 | 4.605 |
| 02:33 ET | 2300 | 4.6 |
| 02:36 ET | 17369 | 4.6 |
| 02:38 ET | 2000 | 4.6 |
| 02:40 ET | 428 | 4.595 |
| 02:42 ET | 400 | 4.595 |
| 02:44 ET | 25297 | 4.6 |
| 02:45 ET | 9451 | 4.584 |
| 02:47 ET | 4200 | 4.585 |
| 02:49 ET | 4469 | 4.585 |
| 02:51 ET | 5249 | 4.555 |
| 02:54 ET | 2608 | 4.555 |
| 02:56 ET | 2800 | 4.555 |
| 02:58 ET | 3300 | 4.555 |
| 03:00 ET | 6684 | 4.55 |
| 03:02 ET | 7151 | 4.5 |
| 03:03 ET | 16786 | 4.48 |
| 03:05 ET | 16341 | 4.48 |
| 03:07 ET | 1702 | 4.48 |
| 03:09 ET | 12157 | 4.485 |
| 03:12 ET | 100 | 4.5 |
| 03:14 ET | 12830 | 4.5 |
| 03:16 ET | 11047 | 4.505 |
| 03:18 ET | 15034 | 4.49 |
| 03:20 ET | 6272 | 4.465 |
| 03:21 ET | 8171 | 4.425 |
| 03:23 ET | 12315 | 4.445 |
| 03:25 ET | 1941 | 4.445 |
| 03:27 ET | 2000 | 4.44 |
| 03:30 ET | 6568 | 4.42 |
| 03:32 ET | 46390 | 4.38 |
| 03:34 ET | 14731 | 4.395 |
| 03:36 ET | 1825 | 4.395 |
| 03:38 ET | 12807 | 4.395 |
| 03:39 ET | 4617 | 4.385 |
| 03:41 ET | 9415 | 4.385 |
| 03:43 ET | 8846 | 4.375 |
| 03:45 ET | 34417 | 4.38 |
| 03:48 ET | 14990 | 4.395 |
| 03:50 ET | 2934 | 4.385 |
| 03:52 ET | 14679 | 4.405 |
| 03:54 ET | 8846 | 4.43 |
| 03:56 ET | 9784 | 4.4 |
| 03:57 ET | 26267 | 4.42 |
| 03:59 ET | 15758 | 4.44 |
| Company sortable | Market Cap sortable | P/E Ratio (TTM) sortable | EPS Growth (5yr) sortable |
|---|---|---|---|
Applied Therapeutics Inc | 529.1M | -2.3x | --- |
Iteos Therapeutics Inc | 537.9M | -3.9x | --- |
SS Innovations International Inc | 546.4M | -29.2x | --- |
Taysha Gene Therapies Inc | 497.5M | -2.1x | --- |
Mind Medicine (MindMed) Inc | 530.4M | -2.4x | --- |
Northwest Biotherapeutics Inc | 545.4M | -7.1x | --- |
Company Information
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
Contact Information
- Headquarters
- 545 FIFTH AVENUE, SUITE 1400NEW YORK, NY, United States 10017
- Phone
- 212-220-9226
- Fax
- 302-636-5454
Executives
- Chairman of the Board, President, Chief Executive Officer, Founder
- Shoshana Shendelman
- Chief Financial Officer and Principal Financial Officer, Director
- Leslie Funtleyder
- Chief Operating Officer and Chief Business Officer
- Constantine Chinoporos
- Chief Accounting Officer
- Catherine Thorpe
- Chief Commercial Officer
- Dale Hooks
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Market Cap | $529.1M |
|---|---|
Revenue (TTM) | $-477.0K |
Shares Outstanding | 114.3M |
Dividend Yield | 0.00% |
Annual Dividend Rate | --- |
Ex-Dividend Date | 01-01-01 |
Pay Date | 01-01-01 |
Beta | 1.99 |
EPS | $-1.91 |
Book Value | $-0.20 |
P/E Ratio | -2.3x |
Price/Sales (TTM) | --- |
Price/Cash Flow (TTM) | --- |
Operating Margin | --- |
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