Applied Therapeutics IncNASDAQ:APLT
- LAST PRICE4.6700
- TODAY'S CHANGE (%)0.0700 (1.5217%)
- Bid / Lots4.5500/ 10
- Ask / Lots4.6600/ 4
- Open / Previous Close4.6000 / 4.6000
- Day Range
- 52 Week Range
- Volume13,783,745
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| Company | Country | Symbol |
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| Time | Volume | APLT |
|---|---|---|
| 09:32 ET | 7444 | 4.615 |
| 09:36 ET | 1700 | 4.65 |
| 09:38 ET | 711 | 4.61 |
| 09:39 ET | 200 | 4.61 |
| 09:41 ET | 1900 | 4.6 |
| 09:43 ET | 200 | 4.59 |
| 09:45 ET | 1361 | 4.64 |
| 09:48 ET | 1814 | 4.61 |
| 09:50 ET | 2300 | 4.58 |
| 09:54 ET | 756 | 4.54 |
| 09:56 ET | 1500 | 4.55 |
| 09:57 ET | 300 | 4.56 |
| 09:59 ET | 1241 | 4.5101 |
| 10:01 ET | 1415 | 4.49 |
| 10:03 ET | 1307 | 4.51 |
| 10:06 ET | 514 | 4.51 |
| 10:08 ET | 1178 | 4.47 |
| 10:10 ET | 1312 | 4.525 |
| 10:12 ET | 1239 | 4.5 |
| 10:14 ET | 600 | 4.51 |
| 10:15 ET | 100 | 4.51 |
| 10:17 ET | 507 | 4.535 |
| 10:19 ET | 849 | 4.57 |
| 10:21 ET | 1718 | 4.55 |
| 10:24 ET | 913 | 4.54 |
| 10:26 ET | 3997 | 4.54 |
| 10:28 ET | 3663 | 4.55 |
| 10:30 ET | 538 | 4.54 |
| 10:32 ET | 2203 | 4.52 |
| 10:33 ET | 3412 | 4.53 |
| 10:35 ET | 2454 | 4.51 |
| 10:37 ET | 3086 | 4.49 |
| 10:39 ET | 3440 | 4.5 |
| 10:42 ET | 1200 | 4.505 |
| 10:44 ET | 1540 | 4.47 |
| 10:46 ET | 300 | 4.48 |
| 10:48 ET | 700 | 4.49 |
| 10:50 ET | 1200 | 4.505 |
| 10:51 ET | 15155 | 4.54 |
| 10:53 ET | 4917 | 4.53 |
| 10:55 ET | 870 | 4.53 |
| 10:57 ET | 3631 | 4.51 |
| 11:00 ET | 935 | 4.515 |
| 11:02 ET | 2110 | 4.505 |
| 11:04 ET | 1302 | 4.5 |
| 11:06 ET | 434 | 4.51 |
| 11:08 ET | 2399 | 4.51 |
| 11:09 ET | 600 | 4.5 |
| 11:11 ET | 1893 | 4.52 |
| 11:13 ET | 254 | 4.51 |
| 11:15 ET | 800 | 4.52 |
| 11:18 ET | 2850 | 4.51 |
| 11:20 ET | 402 | 4.51 |
| 11:22 ET | 6723 | 4.51 |
| 11:24 ET | 1000 | 4.52 |
| 11:26 ET | 2440 | 4.53 |
| 11:27 ET | 800 | 4.54 |
| 11:29 ET | 6115 | 4.55 |
| 11:31 ET | 1200 | 4.54 |
| 11:33 ET | 9068 | 4.57 |
| 11:36 ET | 897 | 4.55 |
| 11:38 ET | 4351 | 4.56 |
| 11:40 ET | 984 | 4.55 |
| 11:42 ET | 2024 | 4.575 |
| 11:44 ET | 3259 | 4.56 |
| 11:45 ET | 1600 | 4.56 |
| 11:47 ET | 2815 | 4.575 |
| 11:49 ET | 1796 | 4.58 |
| 11:51 ET | 500 | 4.585 |
| 11:54 ET | 3452 | 4.6 |
| 11:56 ET | 1920 | 4.625 |
| 11:58 ET | 5335 | 4.624 |
| 12:00 ET | 562 | 4.625 |
| 12:02 ET | 468 | 4.625 |
| 12:03 ET | 1890 | 4.64 |
| 12:05 ET | 1500 | 4.64 |
| 12:07 ET | 1400 | 4.645 |
| 12:09 ET | 2276 | 4.635 |
| 12:12 ET | 1270 | 4.62 |
| 12:14 ET | 4978 | 4.6 |
| 12:16 ET | 200 | 4.59 |
| 12:18 ET | 567 | 4.59 |
| 12:20 ET | 1200 | 4.6 |
| 12:21 ET | 800 | 4.6 |
| 12:23 ET | 4035 | 4.62 |
| 12:25 ET | 1358 | 4.64 |
| 12:27 ET | 1200 | 4.64 |
| 12:30 ET | 2925 | 4.66 |
| 12:32 ET | 1760 | 4.65 |
| 12:34 ET | 12500 | 4.675 |
| 12:38 ET | 2546 | 4.7 |
| 12:39 ET | 9879 | 4.69 |
| 12:41 ET | 200 | 4.68 |
| 12:43 ET | 3249 | 4.68 |
| 12:45 ET | 800 | 4.685 |
| 12:48 ET | 9619 | 4.675 |
| 12:50 ET | 5083 | 4.67 |
| 12:52 ET | 500 | 4.67 |
| 12:54 ET | 4519 | 4.675 |
| 12:56 ET | 1512 | 4.69 |
| 12:57 ET | 700 | 4.695 |
| 12:59 ET | 5495 | 4.7 |
| 01:01 ET | 4520 | 4.69 |
| 01:03 ET | 1352 | 4.7 |
| 01:06 ET | 4882 | 4.71 |
| 01:08 ET | 2225 | 4.7299 |
| 01:10 ET | 500 | 4.725 |
| 01:12 ET | 20504 | 4.7 |
| 01:14 ET | 6504 | 4.695 |
| 01:15 ET | 4200 | 4.675 |
| 01:17 ET | 18076 | 4.7 |
| 01:19 ET | 9819 | 4.7 |
| 01:21 ET | 9727 | 4.63 |
| 01:24 ET | 1863 | 4.62 |
| 01:26 ET | 1764 | 4.62 |
| 01:28 ET | 2406 | 4.625 |
| 01:30 ET | 5947 | 4.609 |
| 01:32 ET | 1200 | 4.605 |
| 01:33 ET | 4712 | 4.605 |
| 01:35 ET | 3356 | 4.61 |
| 01:37 ET | 4919 | 4.6 |
| 01:39 ET | 6760 | 4.62 |
| 01:42 ET | 1400 | 4.6 |
| 01:44 ET | 1640 | 4.61 |
| 01:46 ET | 400 | 4.61 |
| 01:48 ET | 2001 | 4.61 |
| 01:50 ET | 806 | 4.61 |
| 01:51 ET | 2210 | 4.615 |
| 01:53 ET | 3511 | 4.61 |
| 01:55 ET | 767 | 4.61 |
| 01:57 ET | 1500 | 4.615 |
| 02:00 ET | 2146 | 4.615 |
| 02:02 ET | 1133 | 4.615 |
| 02:04 ET | 2020 | 4.61 |
| 02:06 ET | 4278 | 4.605 |
| 02:08 ET | 1544 | 4.605 |
| 02:09 ET | 8662 | 4.63 |
| 02:11 ET | 2608 | 4.65 |
| 02:13 ET | 1843 | 4.64 |
| 02:15 ET | 1559 | 4.65 |
| 02:18 ET | 2447 | 4.68 |
| 02:20 ET | 1400 | 4.68 |
| 02:22 ET | 2200 | 4.68 |
| 02:24 ET | 32086 | 4.68 |
| 02:26 ET | 600 | 4.68 |
| 02:27 ET | 7114 | 4.62 |
| 02:29 ET | 5029 | 4.61 |
| 02:31 ET | 406 | 4.62 |
| 02:33 ET | 800 | 4.61 |
| 02:36 ET | 1824 | 4.62 |
| 02:38 ET | 1493 | 4.62 |
| 02:40 ET | 3286 | 4.62 |
| 02:42 ET | 5306 | 4.63 |
| 02:44 ET | 1909 | 4.63 |
| 02:45 ET | 3168 | 4.625 |
| 02:47 ET | 1452 | 4.625 |
| 02:49 ET | 3271 | 4.62 |
| 02:51 ET | 401 | 4.62 |
| 02:54 ET | 1100 | 4.63 |
| 02:56 ET | 400 | 4.62 |
| 02:58 ET | 1781 | 4.62 |
| 03:00 ET | 1475 | 4.64 |
| 03:02 ET | 2535 | 4.625 |
| 03:03 ET | 4578 | 4.6 |
| 03:05 ET | 615 | 4.59 |
| 03:07 ET | 3176 | 4.61 |
| 03:09 ET | 400 | 4.62 |
| 03:12 ET | 600 | 4.62 |
| 03:14 ET | 1592 | 4.61 |
| 03:16 ET | 2308 | 4.62 |
| 03:18 ET | 1125 | 4.61 |
| 03:20 ET | 6649 | 4.61 |
| 03:21 ET | 1347 | 4.6 |
| 03:23 ET | 400 | 4.605 |
| 03:25 ET | 4109 | 4.615 |
| 03:27 ET | 1377 | 4.615 |
| 03:30 ET | 5928 | 4.615 |
| 03:32 ET | 4587 | 4.615 |
| 03:34 ET | 1135 | 4.62 |
| 03:36 ET | 900 | 4.63 |
| 03:38 ET | 7003 | 4.625 |
| 03:39 ET | 4834 | 4.62 |
| 03:41 ET | 1400 | 4.63 |
| 03:43 ET | 6519 | 4.63 |
| 03:45 ET | 3241 | 4.65 |
| 03:48 ET | 7937 | 4.65 |
| 03:50 ET | 4527 | 4.65 |
| 03:52 ET | 58716 | 4.71 |
| 03:54 ET | 29896 | 4.72 |
| 03:56 ET | 75702 | 4.63 |
| 03:57 ET | 48150 | 4.615 |
| 03:59 ET | 9919621 | 4.67 |
| Company sortable | Market Cap sortable | P/E Ratio (TTM) sortable | EPS Growth (5yr) sortable |
|---|---|---|---|
Applied Therapeutics Inc | 509.6M | -2.4x | --- |
Iteos Therapeutics Inc | 543.3M | -3.9x | --- |
Third Harmonic Bio Inc | 513.9M | -17.4x | --- |
Mind Medicine (MindMed) Inc | 522.5M | -2.5x | --- |
Erasca Inc | 523.6M | -2.8x | --- |
Astria Therapeutics Inc | 493.7M | -3.9x | --- |
Company Information
Applied Therapeutics, Inc. is a clinical-stage biopharmaceutical company. It is focused on developing a pipeline of novel drug candidates against validated molecular targets in indications of high unmet medical need. The Company’s lead drug candidate, govorestat, is a novel central nervous system penetrant Aldose Reductase Inhibitor (ARI) for the treatment of central nervous system (CNS) rare metabolic diseases, including Galactosemia, Sorbitol Dehydrogenase (SORD) Deficiency, and PMM2-CDG. The Company is also developing AT-001, a novel potent ARI, for the treatment of Diabetic Cardiomyopathy (DbCM) a fatal fibrosis of the heart. It has completed a Phase I/II clinical trial evaluating AT-001 in approximately 120 patients with type 2 diabetes, in which no drug-related adverse effects or tolerability issues were observed. The preclinical pipeline also includes AT-003, an ARI designed to cross through the back of the eye when dosed orally, for the treatment of Diabetic retinopathy.
Contact Information
- Headquarters
- 545 FIFTH AVENUE, SUITE 1400NEW YORK, NY, United States 10017
- Phone
- 212-220-9226
- Fax
- 302-636-5454
Executives
- Chairman of the Board, President, Chief Executive Officer, Founder
- Shoshana Shendelman
- Chief Financial Officer and Principal Financial Officer, Director
- Leslie Funtleyder
- Chief Operating Officer and Chief Business Officer
- Constantine Chinoporos
- Interim Principal Financial Officer, Chief Accounting Officer
- Catherine Thorpe
- Chief Commercial Officer
- Dale Hooks
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Market Cap | $509.6M |
|---|---|
Revenue (TTM) | $-477.0K |
Shares Outstanding | 114.3M |
Dividend Yield | 0.00% |
Annual Dividend Rate | --- |
Ex-Dividend Date | 01-01-01 |
Pay Date | 01-01-01 |
Beta | 1.99 |
EPS | $-1.91 |
Book Value | $-0.20 |
P/E Ratio | -2.4x |
Price/Sales (TTM) | --- |
Price/Cash Flow (TTM) | --- |
Operating Margin | --- |
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